This study course covers the key concepts of electronic commerce and its application in logistics area that includes the organization of commercial activities and logistics systems management in the Internet using the modern Web 2.0 and 3.0 technologies, the accent devoting to the B2B, B2C, C2C, C2B and C2G models of the electronic commerce. By characterizing the electronic commerce concepts, the management problems of electronic business, as well as of material, information and financial flows are there examined. In this course, a special attention is paid to the development and implementation technologies, as well as to application and integration principles of electronic commerce systems in logistics and supply chain management by taking into account the activities of Internet service providers, electronic payment methods and e-commerce security problems. During practical lessons, an opportunity to obtain practical skills in the development of e-commerce systems based on an example of B2B Internet shop is there supported.